Abilify and Hyperreflexia - a phase IV clinical study of FDA data

Summary:

Hyperreflexia is reported as a side effect among people who take Abilify (aripiprazole), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Seroquel, and have Psychotic disorder.

The phase IV clinical study analyzes which people have Hyperreflexia when taking Abilify. It is created by eHealthMe based on reports of 97,308 people who have side effects when taking Abilify from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,443 Abilify users. Check the latest studies of Abilify.

What is Hyperreflexia?

Hyperreflexia (overactive or over responsive reflexes) is found to be associated with 499 drugs and 643 conditions by eHealthMe. Check the latest studies of Hyperreflexia.

On Dec, 19, 2025

97,308 people reported to have side effects when taking Abilify.
Among them, 40 people (0.04%) have Hyperreflexia.

Among these 40 people:

How long have people been on Abilify when they have Hyperreflexia? *

What is the gender of people who have Hyperreflexia when taking Abilify? *

female: 72.5 %
male: 27.5 %

What is the age of people who have Hyperreflexia when taking Abilify? *

What are other drugs people take besides Abilify? *

What are other side effects people have besides Hyperreflexia? *

Tremor (trembling or shaking movements in one or more parts of your body): 21 people, 52.50%
Blood Creatine Phosphokinase Increased: 19 people, 47.50%
Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 12 people, 30.00%
Weakness: 11 people, 27.50%
Delirium (wild excitement): 10 people, 25.00%
Hyperhidrosis (abnormally increased sweating): 10 people, 25.00%
Back Pain: 8 people, 20.00%
Fever: 7 people, 17.50%
Muscle Rigidity (muscle stiffness): 7 people, 17.50%
Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 7 people, 17.50%

What are the existing conditions these people have? *

Psychotic Disorder: 9 people, 22.50%
Stress And Anxiety: 7 people, 17.50%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 15.00%
Pain: 6 people, 15.00%
Aggression: 5 people, 12.50%
Agitation (state of anxiety or nervous excitement): 4 people, 10.00%
Muscle Spasms (muscle contraction): 4 people, 10.00%
Diabetes: 4 people, 10.00%
Schizoaffective Disorder (a mental disorder characterized by disordered thought): 3 people, 7.50%
Sleep Apnea Syndrome: 3 people, 7.50%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and have Hyperreflexia?

- Check whether Hyperreflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Abilify:

Abilify (101,443 reports)

Hyperreflexia treatments and more:

Hyperreflexia (4,677 reports)

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperreflexia:

Hyperreflexia (499 drugs)

Browse all the conditions that are associated with Hyperreflexia:

Hyperreflexia (643 conditions)

Drugs similar to Abilify and Hyperreflexia :

Related publications that referenced our studies

Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .
Cetin, M., Celik, M., Cakici, M., Polat, M., & Suner, A, "Aripiprazole-Induced Hoarseness", Turk Psikiyatri Dergisi, 2018 Jan .
Cetin M, Celik M, Cakici M, Polat M, Suner A, "Aripiprazole induced non-cardiogenic pulmonary edema: a case report", Turk Psikiyatri Dergisi, 2014 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole (the active ingredients of Abilify) and Abilify (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.