Acetaminophen and codeine phosphate and Heart palpitations - a phase IV clinical study of FDA data

Summary:

Heart palpitations is reported as a side effect among people who take Acetaminophen and codeine phosphate (acetaminophen; codeine phosphate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Omeprazole, and have Hypertonic bladder.

The phase IV clinical study analyzes which people have Heart palpitations when taking Acetaminophen and codeine phosphate. It is created by eHealthMe based on reports of 2,908 people who have side effects when taking Acetaminophen and codeine phosphate from the FDA, and is updated regularly.

What is Acetaminophen and codeine phosphate?

Acetaminophen and codeine phosphate has active ingredients of acetaminophen; codeine phosphate. It is often used in pain. eHealthMe is studying from 3,220 Acetaminophen and codeine phosphate users. Check the latest studies of Acetaminophen and codeine phosphate.

What is Heart palpitations?

Heart palpitations (feelings or sensations that your heart is pounding or racing) is found to be associated with 2,436 drugs and 3,638 conditions by eHealthMe. Check the latest studies of Heart palpitations.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

2,908 people reported to have side effects when taking Acetaminophen and codeine phosphate.
Among them, 25 people (0.86%) have Heart palpitations.

Could Acetaminophen and codeine phosphate cause Heart palpitations?

Among these 25 people:

How long have people been on Acetaminophen and codeine phosphate when they have Heart palpitations? *

What is the gender of people who have Heart palpitations when taking Acetaminophen and codeine phosphate? *

female: 56 %
male: 44 %

What is the age of people who have Heart palpitations when taking Acetaminophen and codeine phosphate? *

What are other drugs people take besides Acetaminophen and codeine phosphate? *

Omeprazole: 9 people, 36.00%
Acetaminophen: 7 people, 28.00%
Diazepam: 7 people, 28.00%
Ranitidine: 6 people, 24.00%
Perindopril Erbumine: 6 people, 24.00%
Mirtazapine: 5 people, 20.00%
Citalopram Hydrobromide: 5 people, 20.00%
Ventolin: 5 people, 20.00%
Aspirin: 4 people, 16.00%
Prednisolone: 4 people, 16.00%

What are other side effects people have besides Heart palpitations? *

Dizziness: 11 people, 44.00%
Indigestion: 7 people, 28.00%
Hyperhidrosis (abnormally increased sweating): 6 people, 24.00%
Dyspnea (difficult or laboured breathing): 5 people, 20.00%
Fatigue (feeling of tiredness): 5 people, 20.00%
Malaise (a feeling of general discomfort or uneasiness): 5 people, 20.00%
Dyspnea Exertional: 4 people, 16.00%
Dry Eyes (lack of adequate tears): 4 people, 16.00%
Diarrhea: 4 people, 16.00%
Oedema Peripheral (superficial swelling): 4 people, 16.00%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 4 people, 16.00%
Stress And Anxiety: 3 people, 12.00%
Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 3 people, 12.00%
High Blood Pressure: 3 people, 12.00%
Diabetes: 3 people, 12.00%
High Blood Cholesterol: 2 people, 8.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 4.00%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 1 person, 4.00%
Macular Oedema (fluid and protein deposits collect on or under the macula of the eye (a yellow central area of the retina) and causes it to thicken): 1 person, 4.00%
Fungal Nail Infection: 1 person, 4.00%

* Approximation only. Some reports may have incomplete information.

Do you take Acetaminophen and codeine phosphate and have Heart palpitations?

- Check whether Heart palpitations is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Acetaminophen and codeine phosphate:

Acetaminophen and codeine phosphate (3,220 reports)

Heart palpitations treatments and more:

Heart palpitations (147,653 reports)

How severe was Heart palpitations and when was it recovered:

Heart palpitations in Acetaminophen and codeine phosphate

Expand to all the drugs that have ingredients of acetaminophen; codeine phosphate:

Heart palpitations and drugs with ingredients of acetaminophen; codeine phosphate (691 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acetaminophen and codeine phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart palpitations:

Heart palpitations (2,436 drugs)

Browse all the conditions that are associated with Heart palpitations:

Heart palpitations (3,638 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen; codeine phosphate (the active ingredients of Acetaminophen and codeine phosphate) and Acetaminophen and codeine phosphate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.