Advil and Hypercoagulation - a phase IV clinical study of FDA data

Summary:

Hypercoagulation is reported as a side effect among people who take Advil (ibuprofen), especially for people who are female, 40-49 old, also take Tylenol, and have Ovarian cancer.

The phase IV clinical study analyzes which people have Hypercoagulation when taking Advil. It is created by eHealthMe based on reports of 60,378 people who have side effects when taking Advil from the FDA, and is updated regularly.

What is Advil?

Advil has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 62,532 Advil users. Check the latest studies of Advil.

What is Hypercoagulation?

Hypercoagulation (increased tendency for clotting of the blood) is found to be associated with 425 drugs and 533 conditions by eHealthMe. Check the latest studies of Hypercoagulation.

On Nov, 18, 2025

60,378 people reported to have side effects when taking Advil.
Among them, 33 people (0.05%) have Hypercoagulation.

Among these 33 people:

What is the gender of people who have Hypercoagulation when taking Advil? *

female: 87.88 %
male: 12.12 %

What is the age of people who have Hypercoagulation when taking Advil? *

What are other drugs people take besides Advil? *

What are other side effects people have besides Hypercoagulation? *

Depression: 14 people, 42.42%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 10 people, 30.30%
Weight Increased: 9 people, 27.27%
Insomnia (sleeplessness): 8 people, 24.24%
Hot Flush (sudden feelings of heat): 8 people, 24.24%
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 7 people, 21.21%
Abdominal Pain: 7 people, 21.21%
Nausea (feeling of having an urge to vomit): 7 people, 21.21%
Head Injury: 7 people, 21.21%
Rashes (redness): 7 people, 21.21%

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 10 people, 30.30%
Birth Control: 6 people, 18.18%
Sinusitis (inflammation of sinus): 5 people, 15.15%
Stress And Anxiety: 4 people, 12.12%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 3 people, 9.09%
Weight Decreased: 2 people, 6.06%
Asthma: 2 people, 6.06%
Hypersensitivity: 1 person, 3.03%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 3.03%
Hepatitis B: 1 person, 3.03%

* Approximation only. Some reports may have incomplete information.

Do you take Advil and have Hypercoagulation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Advil:

Advil (62,532 reports)

Browse all side effects of Advil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypercoagulation:

Hypercoagulation (425 drugs)

Browse all the conditions that are associated with Hypercoagulation:

Hypercoagulation (533 conditions)

Drugs similar to Advil and Hypercoagulation :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Advil) and Advil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.