Altace and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Altace (ramipril), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Digoxin, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Altace. It is created by eHealthMe based on reports of 23,086 people who have side effects when taking Altace from the FDA, and is updated regularly.

What is Altace?

Altace has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 23,681 Altace users. Check the latest studies of Altace.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,181 drugs and 840 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Jan, 19, 2026

23,086 people reported to have side effects when taking Altace.
Among them, 31 people (0.13%) have Sinus node dysfunction.

Could Altace cause Sinus node dysfunction?

Among these 31 people:

How long have people been on Altace when they have Sinus node dysfunction? *

What is the gender of people who have Sinus node dysfunction when taking Altace? *

female: 51.61 %
male: 48.39 %

What is the age of people who have Sinus node dysfunction when taking Altace? *

What are other drugs people take besides Altace? *

What are other side effects people have besides Sinus node dysfunction? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 15 people, 48.39%
Dizziness: 12 people, 38.71%
Weight Decreased: 10 people, 32.26%
Cardiac Failure Congestive: 10 people, 32.26%
Hyperlipidaemia (presence of excess lipids in the blood): 9 people, 29.03%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 8 people, 25.81%
Weakness: 8 people, 25.81%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 8 people, 25.81%
Nausea (feeling of having an urge to vomit): 8 people, 25.81%
Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 7 people, 22.58%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 19.35%
Diabetes: 3 people, 9.68%
Hepatitis C: 2 people, 6.45%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 6.45%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.23%
Osteoporosis (bones weak and more likely to break): 1 person, 3.23%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 3.23%
Microalbuminuria (albumin into the urine): 1 person, 3.23%
Metastases To Bone (cancer spreads to bone): 1 person, 3.23%
Heart Rate Increased: 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Altace and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Altace:

Altace (23,681 reports)

Browse all side effects of Altace:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,181 drugs)

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (840 conditions)

Drugs similar to Altace and Sinus node dysfunction :

How the study uses the data?

The study uses data from the FDA. It is based on ramipril (the active ingredients of Altace) and Altace (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.