Norvasc and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Norvasc (amlodipine besylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Lasix, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Norvasc. It is created by eHealthMe based on reports of 133,505 people who have side effects when taking Norvasc from the FDA, and is updated regularly.

What is Norvasc?

Norvasc has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 136,737 Norvasc users. Check the latest studies of Norvasc.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,178 drugs and 840 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.



On Jan, 31, 2026

133,505 people reported to have side effects when taking Norvasc.
Among them, 171 people (0.13%) have Sinus node dysfunction.

Could Norvasc cause Sinus node dysfunction?

Among these 171 people:

How long have people been on Norvasc when they have Sinus node dysfunction? *

What is the gender of people who have Sinus node dysfunction when taking Norvasc? *

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What is the age of people who have Sinus node dysfunction when taking Norvasc? *

What are other drugs people take besides Norvasc? *

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What are other side effects people have besides Sinus node dysfunction? *

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What are the existing conditions these people have? *

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* Approximation only. Some reports may have incomplete information.

Do you take Norvasc and have Sinus node dysfunction?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Norvasc:

Sinus node dysfunction treatments and more:

How severe was Sinus node dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of amlodipine besylate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Norvasc side effects:

Browse all side effects of Norvasc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sinus node dysfunction:

Browse all the drugs that are associated with Sinus node dysfunction:

Common conditions associated with Sinus node dysfunction:

Browse all the conditions that are associated with Sinus node dysfunction:

Drugs similar to Norvasc and Sinus node dysfunction :


How the study uses the data?

The study uses data from the FDA. It is based on amlodipine besylate (the active ingredients of Norvasc) and Norvasc (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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