Creon and Autoimmune disorder - a phase IV clinical study of FDA data

Summary:

Autoimmune disorder is reported as a side effect among people who take Creon (pancrelipase (amylase;lipase;protease)), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Naltrexone, and have Hypogammaglobulinaemia.

The phase IV clinical study analyzes which people have Autoimmune disorder when taking Creon. It is created by eHealthMe based on reports of 29,220 people who have side effects when taking Creon from the FDA, and is updated regularly.

What is Creon?

Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.

What is Autoimmune disorder?

Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue) is found to be associated with 721 drugs and 822 conditions by eHealthMe. Check the latest studies of Autoimmune disorder.

On Jul, 11, 2026

29,220 people reported to have side effects when taking Creon.
Among them, 29 people (0.1%) have Autoimmune disorder.

Among these 29 people:

How long have people been on Creon when they have Autoimmune disorder? *

What is the gender of people who have Autoimmune disorder when taking Creon? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Autoimmune disorder when taking Creon? *

What are other drugs people take besides Creon? *

Naltrexone: 9 people, 31.03%
Bactrim: 6 people, 20.69%
Lyrica: 6 people, 20.69%
Sodium Chloride: 5 people, 17.24%
Fish Oil: 5 people, 17.24%
Heparin: 5 people, 17.24%
Lidoderm: 4 people, 13.79%
Naltrexone Hydrochloride: 4 people, 13.79%
Morphine: 4 people, 13.79%
Lunesta: 4 people, 13.79%

What are other side effects people have besides Autoimmune disorder? *

Nausea And Vomiting: 7 people, 24.14%
Diarrhea: 7 people, 24.14%
Malaise (a feeling of general discomfort or uneasiness): 7 people, 24.14%
Dark Circles Under Eyes: 6 people, 20.69%
Cat Scratch Disease (bacterial infection by cat scratch): 5 people, 17.24%
Mycotic Allergy (fungal allergy): 5 people, 17.24%
Migraine (headache): 5 people, 17.24%
Lyme Disease (a bacterial infection that is spread to humans by infected ticks): 5 people, 17.24%
Rashes (redness): 4 people, 13.79%
Fatigue (feeling of tiredness): 4 people, 13.79%

What are the existing conditions these people have? *

Primary Immunodeficiency Syndrome: 5 people, 17.24%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 17.24%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 17.24%
Immunodeficiency Common Variable: 5 people, 17.24%
Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 5 people, 17.24%
Diabetes: 3 people, 10.34%
Pancreatic Disorder: 2 people, 6.90%
Nerve Injury: 2 people, 6.90%
Drowsiness: 2 people, 6.90%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 3.45%

* Approximation only. Some reports may have incomplete information.

Do you take Creon and have Autoimmune disorder?

- Check whether Autoimmune disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Creon:

Creon (29,489 reports)

Autoimmune disorder treatments and more:

Autoimmune disorder (12,834 reports)

How severe was Autoimmune disorder and when was it recovered:

Autoimmune disorder in Creon

Expand to all the drugs that have ingredients of pancrelipase (amylase;lipase;protease):

Autoimmune disorder and drugs with ingredients of pancrelipase (amylase;lipase;protease)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Creon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Autoimmune disorder:

Autoimmune disorder (721 drugs)

Browse all the conditions that are associated with Autoimmune disorder:

Autoimmune disorder (822 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on pancrelipase (amylase;lipase;protease) (the active ingredients of Creon) and Creon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.