Gleevec and Icterus - a phase IV clinical study of FDA data
Summary:
Icterus is reported as a side effect among people who take Gleevec (imatinib mesylate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Xanax, and have Gastrointestinal stromal tumor.
The phase IV clinical study analyzes which people have Icterus when taking Gleevec. It is created by eHealthMe based on reports of 35,000 people who have side effects when taking Gleevec from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Icterus?
Icterus (yellowish pigmentation of the skin) is found to be associated with 2,125 drugs and 2,998 conditions by eHealthMe. Check the latest studies of Icterus.
35,000 people reported to have side effects when taking Gleevec.
Among them, 150 people (0.43%) have Icterus.

Among these 150 people:
How long have people been on Gleevec when they have Icterus? *
What is the gender of people who have Icterus when taking Gleevec? *
What is the age of people who have Icterus when taking Gleevec? *
What are other drugs people take besides Gleevec? *
What are other side effects people have besides Icterus? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and have Icterus?
- Check whether Icterus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Gleevec:
- Gleevec (35,415 reports)
Icterus treatments and more:
- Icterus (33,621 reports)
How severe was Icterus and when was it recovered:
Expand to all the drugs that have ingredients of imatinib mesylate:
- Icterus and drugs with ingredients of imatinib mesylate (272 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Gleevec side effects:
- Gleevec side effect: Death (5,026 reports)
- Gleevec side effect: Malaise (a feeling of general discomfort or uneasiness) (1,536 reports)
- Gleevec side effect: Drug ineffective (1,514 reports)
- Gleevec side effect: Dyspnea (difficult or laboured breathing) (1,452 reports)
- Gleevec side effect: Muscle spasms (muscle contraction) (1,272 reports)
- Gleevec side effect: Anaemia (lack of blood) (1,247 reports)
- Gleevec side effect: Neoplasm malignant (cancer tumour) (1,082 reports)
- Gleevec side effect: Oedema peripheral (superficial swelling) (1,010 reports)
- Gleevec side effect: Malignant neoplasm progression (cancer tumour came back) (991 reports)
- Gleevec side effect: Haemoglobin decreased (983 reports)
- Gleevec side effect: Pneumonia (908 reports)
- Gleevec side effect: Pleural effusion (water on the lungs) (845 reports)
- Gleevec side effect: White blood cell count decreased (795 reports)
- Gleevec side effect: Fluid retention (an abnormal accumulation of fluid in the blood) (738 reports)
- Gleevec side effect: Fall (697 reports)
- Gleevec side effect: Oedema (fluid collection in tissue) (686 reports)
- Gleevec side effect: Acute kidney failure (683 reports)
- Gleevec side effect: Pain in extremity (670 reports)
- Gleevec side effect: Muscle aches (muscle pain) (654 reports)
- Gleevec side effect: Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood) (590 reports)
- Gleevec side effect: Chest pain (545 reports)
- Gleevec side effect: Blood creatinine increased (539 reports)
- Gleevec side effect: Abdominal discomfort (536 reports)
- Gleevec side effect: Bone pain (533 reports)
- Gleevec side effect: White blood cell count increased (525 reports)
- Gleevec side effect: Back pain (519 reports)
- Gleevec side effect: Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection) (501 reports)
- Gleevec side effect: Hypotension (abnormally low blood pressure) (487 reports)
- Gleevec side effect: Eye swelling (465 reports)
- Gleevec side effect: Swelling (441 reports)
- Gleevec side effect: Disease progression (436 reports)
- Gleevec side effect: Dehydration (dryness resulting from the removal of water) (421 reports)
- Gleevec side effect: Drug intolerance (drug sensitivity) (419 reports)
- Gleevec side effect: Nasopharyngitis (inflammation of the nasopharynx) (407 reports)
- Gleevec side effect: Periorbital oedema (swelling around the eyes) (401 reports)
- Gleevec side effect: Sepsis (a severe blood infection that can lead to organ failure and death) (400 reports)
- Gleevec side effect: Neoplasm progression (growth of tumour) (392 reports)
- Gleevec side effect: Infection (390 reports)
- Gleevec side effect: Abdominal distension (384 reports)
- Gleevec side effect: Aspartate aminotransferase increased (383 reports)
- Gleevec side effect: Alanine aminotransferase increased (371 reports)
- Gleevec side effect: Gait disturbance (369 reports)
- Gleevec side effect: General physical health deterioration (weak health status) (365 reports)
- Gleevec side effect: Face oedema (swelling of face) (361 reports)
- Gleevec side effect: Ascites (accumulation of fluid in the abdominal cavity) (356 reports)
- Gleevec side effect: Hypoaesthesia (reduced sense of touch or sensation) (352 reports)
- Gleevec side effect: Peripheral swelling (343 reports)
- Gleevec side effect: Red blood cell count decreased (341 reports)
- Gleevec side effect: Cardiac failure congestive (338 reports)
- Gleevec side effect: Swelling face (334 reports)
- Gleevec side effect: Urinary tract infection (317 reports)
- Gleevec side effect: Cardiac disorder (307 reports)
- Gleevec side effect: Hypoacusis (loss of hearing) (304 reports)
- Gleevec side effect: Haematocrit decreased (303 reports)
- Gleevec side effect: Surgery (301 reports)
- Gleevec side effect: Leukaemia (blood or bone marrow cancer) (296 reports)
- Gleevec side effect: Blast crisis in myelogenous leukaemia (294 reports)
- Gleevec side effect: Drug exposure during pregnancy (293 reports)
- Gleevec side effect: Renal impairment (severely reduced kidney function) (292 reports)
- Gleevec side effect: Eyelid oedema (eyelids are swollen and contain excessive fluid) (286 reports)
- Gleevec side effect: Blood lactate dehydrogenase increased (282 reports)
- Gleevec side effect: Interstitial lung disease (279 reports)
- Gleevec side effect: Chills (felling of cold) (276 reports)
- Gleevec side effect: Vision blurred (272 reports)
- Gleevec side effect: Metastases to liver (cancer spreads to liver) (271 reports)
- Gleevec side effect: Loss of consciousness (260 reports)
- Gleevec side effect: Drug resistance (reduction in effectiveness of a drug) (247 reports)
- Gleevec side effect: Renal disorder (kidney disease) (245 reports)
- Gleevec side effect: Pulmonary oedema (fluid accumulation in the lungs) (241 reports)
- Gleevec side effect: Confusional state (237 reports)
- Gleevec side effect: Pericardial effusion (fluid around the heart) (232 reports)
- Gleevec side effect: Eye haemorrhage (bleeding in the eye) (229 reports)
- Gleevec side effect: Diabetes (226 reports)
- Gleevec side effect: Visual impairment (219 reports)
- Gleevec side effect: Lung disorder (lung disease) (215 reports)
- Gleevec side effect: Neuropathy peripheral (surface nerve damage) (213 reports)
- Gleevec side effect: Bone marrow failure (210 reports)
- Gleevec side effect: Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure) (208 reports)
- Gleevec side effect: Leukopenia (less number of white blood cells in blood) (205 reports)
- Gleevec side effect: Blood creatine phosphokinase increased (202 reports)
- Gleevec side effect: Lacrimation increased (200 reports)
- Gleevec side effect: Second primary malignancy (after getting cure a cancer, a new cancer development) (198 reports)
- Gleevec side effect: Gastrointestinal disorder (functional problems of gastrointestinal tract) (195 reports)
- Gleevec side effect: Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight) (194 reports)
- Gleevec side effect: Splenomegaly (enlargement of spleen) (193 reports)
- Gleevec side effect: Haematochezia (passage of stools containing blood) (192 reports)
- Gleevec side effect: Liver disorder (liver diseases) (187 reports)
- Gleevec side effect: Urticaria (rash of round, red welts on the skin that itch intensely) (186 reports)
- Gleevec side effect: Gamma-glutamyltransferase increased (182 reports)
- Gleevec side effect: Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect) (181 reports)
- Gleevec side effect: Blood glucose increased (180 reports)
- Gleevec side effect: Blood urea increased (179 reports)
- Gleevec side effect: C-reactive protein increased (176 reports)
- Gleevec side effect: Skin exfoliation (removal of the oldest dead skin cells) (170 reports)
- Gleevec side effect: Flatulence (flatus expelled through the anus) (167 reports)
- Gleevec side effect: Intestinal obstruction (164 reports)
- Gleevec side effect: Hearing loss (158 reports)
- Gleevec side effect: Recurrent cancer (repeated cancer) (157 reports)
- Gleevec side effect: Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves) (151 reports)
- Gleevec side effect: Leukocytosis (increased white blood cells) (149 reports)
- Gleevec side effect: Oropharyngeal pain (148 reports)
- Gleevec side effect: Hoarseness or changing voice (145 reports)
- Gleevec side effect: Hepatic enzyme increased (142 reports)
- Gleevec side effect: Hepatic failure (liver failure) (141 reports)
- Gleevec side effect: Lymph follicular hypertrophy (an increase in the size of the lymph node follicles) (140 reports)
- Gleevec side effect: Stomatitis (inflammation of mucous membrane of mouth) (138 reports)
- Gleevec side effect: Blood potassium decreased (137 reports)
- Gleevec side effect: Herpes zoster (136 reports)
- Gleevec side effect: Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body) (135 reports)
- Gleevec side effect: Low tissue oxygen (134 reports)
- Gleevec side effect: Septic shock (shock due to blood infection) (131 reports)
- Gleevec side effect: Prostate cancer (130 reports)
- Gleevec side effect: Cardiac arrest (128 reports)
- Gleevec side effect: Therapeutic response decreased (less preventive response) (125 reports)
- Gleevec side effect: Hypokalemia (low potassium) (124 reports)
- Gleevec side effect: Leukaemia recurrent (repeat cancer of bone marrow or blood cells) (119 reports)
- Gleevec side effect: Hip fracture (115 reports)
- Gleevec side effect: Ejection fraction decreased (systolic heart failure) (113 reports)
- Gleevec side effect: Urination - painful (112 reports)
- Gleevec side effect: Cellulitis (infection under the skin) (111 reports)
- Gleevec side effect: Rectal haemorrhage (bleeding from anus) (109 reports)
- Gleevec side effect: Night sweats (sweating in night) (108 reports)
- Gleevec side effect: Speech disorder (107 reports)
- Gleevec side effect: Tumor lysis syndrome (105 reports)
- Gleevec side effect: Gallstones (stone formation by bile component) (103 reports)
- Gleevec side effect: Inflammation (102 reports)
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Icterus:
- Aspirin (1,442 reports)
- Prednisone (1,384 reports)
- Omeprazole (1,101 reports)
- Furosemide (1,064 reports)
- Metformin (1,044 reports)
- Profen (954 reports)
- Pantoprazole (880 reports)
- Augmentin (878 reports)
- Prednisolone (875 reports)
- Amlodipine (850 reports)
- Ramipril (848 reports)
- Ibu (792 reports)
- Lansoprazole (788 reports)
- Ibuprofen (784 reports)
- Lopurin (763 reports)
- Ribavirin (757 reports)
- Paracetamol (745 reports)
- Lipitor (740 reports)
- Lasix (722 reports)
- Acetaminophen (716 reports)
- Methotrexate (705 reports)
- Simvastatin (648 reports)
- Allopurinol (630 reports)
- Amoxicillin (586 reports)
- Spironolactone (566 reports)
- Isoniazid (538 reports)
- Soliris (522 reports)
- Atenolol (512 reports)
- Nexium (483 reports)
- Humira (477 reports)
- Digoxin (474 reports)
- Tylenol (467 reports)
- Sandostatin (457 reports)
- Folic acid (432 reports)
- Loraz (426 reports)
- Zide (425 reports)
- Bactrim (423 reports)
- Acetylsalicylic acid (418 reports)
- Nexavar (412 reports)
- Zoloft (396 reports)
- Ketek (392 reports)
- Lisinopril (386 reports)
- Sutent (382 reports)
- Cyclophosphamide (373 reports)
- Fluorouracil (367 reports)
- Reyataz (363 reports)
- Levothyroxine sodium (361 reports)
- Morphine (359 reports)
- Hydrochlorothiazide (355 reports)
- Truvada (348 reports)
- Augmentin '125' (346 reports)
- Tramadol (345 reports)
- Lactulose (340 reports)
- Xarelto (337 reports)
- Cymbalta (329 reports)
- Vitamins (325 reports)
- Celebrex (323 reports)
- Xanax (322 reports)
- Oxaliplatin (318 reports)
- Sandostatin lar (315 reports)
- Dexamethasone (312 reports)
- Clarithromycin (309 reports)
- Aldactone (307 reports)
- Ondansetron (296 reports)
- Lyrica (289 reports)
- Pyrazinamide (286 reports)
- Synthroid (284 reports)
- Ranitidine (282 reports)
- Norvir (281 reports)
- Lantus (279 reports)
- Gabapentin (278 reports)
- Famotidine (277 reports)
- Zofran (273 reports)
- Norvasc (272 reports)
- Fluconazole (271 reports)
- Xeloda (267 reports)
- Tacrolimus (265 reports)
- Sertraline (261 reports)
- Levaquin (258 reports)
- Kaletra (248 reports)
- Losartan (247 reports)
- Albuterol (244 reports)
- Ursodiol (243 reports)
- Pegasys (242 reports)
- Heparin (236 reports)
- Clopidogrel (232 reports)
- Capecitabine (230 reports)
- Coumadin (229 reports)
- Votrient (227 reports)
- Arava (226 reports)
- Eliquis (225 reports)
- Lamictal (223 reports)
- Atorvastatin calcium (222 reports)
- Pantoprazole sodium (220 reports)
- Carboplatin (219 reports)
- Ambien (218 reports)
- Cyclosporine (215 reports)
- Alprazolam (214 reports)
- Fosamax (211 reports)
- Ceftriaxone (210 reports)
- Indapamide (209 reports)
- Letrozole (208 reports)
- Singulair (206 reports)
- Keppra (205 reports)
- Enbrel (201 reports)
- Fenofibrate (199 reports)
- Zolpidem (198 reports)
- Remicade (195 reports)
- Zometa (194 reports)
- Meropenem (193 reports)
- Nifedipine (192 reports)
- Solu-medrol (191 reports)
- Mirtazapine (188 reports)
- Naproxen (187 reports)
- Zantac (186 reports)
- Sovaldi (179 reports)
- Lamisil (178 reports)
- Amlodipine besylate (177 reports)
- Neurontin (176 reports)
- Prilosec (175 reports)
- Etoposide (173 reports)
- Fentanyl (169 reports)
- Benadryl (168 reports)
- Seroquel (167 reports)
- Micardis (166 reports)
- Allegra (165 reports)
- Viread (164 reports)
- Irbesartan (162 reports)
- Avelox (160 reports)
- Gemcitabine (159 reports)
- Paxil (158 reports)
- Decadron (156 reports)
- Diflucan (155 reports)
- Neoral (154 reports)
- Prozac (153 reports)
- Cordarone (152 reports)
- Escitalopram (151 reports)
- Cisplatin (150 reports)
- Avandia (149 reports)
- Valsartan (148 reports)
- Paclitaxel (147 reports)
- Tasigna (146 reports)
- Torsemide (145 reports)
- Avonex (143 reports)
- Clonazepam (142 reports)
- Risperdal (140 reports)
- Valtrex (137 reports)
- Diclofenac sodium (136 reports)
- Glucophage (135 reports)
- Sofosbuvir (134 reports)
- Pregabalin (133 reports)
- Paroxetine (132 reports)
- Stivarga (130 reports)
- Somavert (129 reports)
- Propofol (128 reports)
- Vitamin b12 (127 reports)
- Keytruda (126 reports)
- Atarax (125 reports)
- Esomeprazole magnesium (124 reports)
- Amoxicillin and clavulanate potassium (123 reports)
- Strattera (122 reports)
- Pepcid (121 reports)
- Wellbutrin (120 reports)
- Herceptin (118 reports)
- Diphen (117 reports)
- Hydramine (116 reports)
- Gliclazide (115 reports)
- Imodium (114 reports)
- Thiamine (113 reports)
- Clonidine (112 reports)
- Fulvestrant (111 reports)
- Yasmin (110 reports)
- Zithromax (109 reports)
- Opdivo (107 reports)
- Peg-intron (106 reports)
- Olanzapine (105 reports)
- Efavirenz (104 reports)
- Actonel (103 reports)
- Morphine sulfate (102 reports)
- Risperidone (101 reports)
Browse all the drugs that are associated with Icterus:
- Icterus (2,125 drugs)
Common conditions associated with Icterus:
- Hbp: 2,055 reports
- Hiv antibody positive: 1,017 reports
- Hiv: 1,000 reports
- Hiv test: 978 reports
- Hepatitis c: 954 reports
- Pain exacerbated: 856 reports
- Depression: 850 reports
- Hypnosis and pain: 832 reports
- Antidepressant therapy: 830 reports
- Arthritis - rheumatoid: 682 reports
- Diabetes mellitus: 676 reports
- Type 2 diabetes: 667 reports
- Rheumatoid arthritis: 663 reports
- Hyperlipidemia: 614 reports
- Acupuncture and pain: 573 reports
- Multiple sclerosis aggravated: 558 reports
- Preventive health care: 502 reports
- Breast cancer aggravated: 491 reports
- Paroxysmal nocturnal haemoglobinuria: 489 reports
- A-fib: 465 reports
- Lipid profile: 441 reports
- Urinary tract infection: 423 reports
- Reduce cholesterol: 419 reports
- Infection: 405 reports
- Lower cholesterol: 399 reports
- Osteoporosis: 396 reports
- Thin bones: 368 reports
- Breast cancer metastatic: 364 reports
- Cancer - liver: 331 reports
- Renal cancer: 327 reports
- Anxiety aggravated: 323 reports
- Peptic esophagitis: 311 reports
- Chronic myeloid leukaemia: 306 reports
- Plasmacytoma of bone: 304 reports
- Heartburn - chronic: 303 reports
- Hepatic neoplasm malignant: 297 reports
- Nausea: 296 reports
- Psoriasis: 295 reports
- Hypothyroidy: 291 reports
- Cannot sleep: 287 reports
- Epilepsy: 284 reports
- Seizure disorder: 283 reports
- Tuberculosis: 278 reports
- Regional enteritis: 276 reports
- Cancer - colon: 263 reports
- Thrombosis: 243 reports
- Sinusitis: 241 reports
- Sinus infection: 236 reports
- Familial primary pulmonary hypertension: 234 reports
- Pain - back: 233 reports
- Back pain aggravated: 231 reports
- Pneumonia: 227 reports
- Inflammation - bronchi: 225 reports
- Constipation: 220 reports
- Family planning and contraception: 219 reports
- Bronchopneumonia: 216 reports
- Gastritis aggravated: 215 reports
- Sinusitis - acute: 211 reports
- Chronic asthma: 210 reports
- Pyrexia: 209 reports
- Stool softener needs: 208 reports
- Hepatic cirrhosis: 205 reports
- Elevated temperature: 203 reports
- Colorectal cancer metastatic: 184 reports
- Prostate cancer: 181 reports
- Ill-defined disorder: 176 reports
- Stroke: 172 reports
- Dyslipidaemia: 170 reports
- Ulcer - stomach: 168 reports
- Schizophrenia: 167 reports
- Duodenal ulcer: 165 reports
- Stomach acid test: 162 reports
- Psoriatic arthropathy aggravated: 157 reports
- Hyperuricaemia: 156 reports
- Acromegaly: 154 reports
- Upset stomach: 152 reports
- Acute myeloid leukaemia: 151 reports
- Transplant - liver: 149 reports
- Liver transplant: 147 reports
- Spondylarthropathy: 141 reports
- Ankylosing spondylitis: 140 reports
- Anaemia: 137 reports
- Pulmonary hypertension: 135 reports
- Gastrointestinal stromal tumour: 133 reports
- Chronic lymphocytic leukaemia: 129 reports
- Ulcerative colitis: 128 reports
- Lung cancer - non-small cell: 127 reports
- Convulsion: 125 reports
- Antiviral: 124 reports
- Joint inflammation: 122 reports
- Bone and joint pain: 117 reports
- Joint pain: 115 reports
- Foetal exposure during pregnancy: 114 reports
- Neuroendocrine tumour: 112 reports
- Acute lymphocytic leukemia (all): 111 reports
- Frequent headaches: 108 reports
- Emesis: 107 reports
- Bhp: 106 reports
- Pancreatic carcinoma: 105 reports
- Nasopharyngitis: 103 reports
- Bipolar: 102 reports
- Sleep disorder due to a general medical condition: 101 reports
Browse all the conditions that are associated with Icterus:
- Icterus (2,998 conditions)
Related publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate (the active ingredients of Gleevec) and Gleevec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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