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Metformin and Bone neoplasm malignant - a phase IV clinical study of FDA data

Summary:

Bone neoplasm malignant is reported as a side effect among people who take Metformin (metformin hydrochloride), especially for people who are female, 60+ old, also take Zometa, and have Lung neoplasm malignant.

The phase IV clinical study analyzes which people have Bone neoplasm malignant when taking Metformin. It is created by eHealthMe based on reports of 453,860 people who have side effects when taking Metformin from the FDA, and is updated regularly.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,358 Metformin users. Check the latest studies of Metformin.

What is Bone neoplasm malignant?

Bone neoplasm malignant (cancer of bone) is found to be associated with 292 drugs and 214 conditions by eHealthMe. Check the latest studies of Bone neoplasm malignant.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

453,860 people reported to have side effects when taking Metformin.
Among them, 24 people (0.01%) have Bone neoplasm malignant.

Could Metformin cause Bone neoplasm malignant?

Among these 24 people:

What is the gender of people who have Bone neoplasm malignant when taking Metformin? *

  • female: 70.83 %
  • male: 29.17 %

What is the age of people who have Bone neoplasm malignant when taking Metformin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 4.17 %
  • 40-49: 41.67 %
  • 50-59: 0.0 %
  • 60+: 54.17 %

What are other drugs people take besides Metformin? *

  1. Zometa: 20 people, 83.33%
  2. Vicodin: 11 people, 45.83%
  3. Oxycontin: 10 people, 41.67%
  4. Revlimid: 9 people, 37.50%
  5. Zocor: 8 people, 33.33%
  6. Celexa: 8 people, 33.33%
  7. Aspirin: 8 people, 33.33%
  8. Omeprazole: 8 people, 33.33%
  9. Simvastatin: 8 people, 33.33%
  10. Lisinopril: 7 people, 29.17%

What are other side effects people have besides Bone neoplasm malignant? *

  1. Pain: 20 people, 83.33%
  2. Stress And Anxiety: 20 people, 83.33%
  3. Injury: 17 people, 70.83%
  4. Emotional Distress: 17 people, 70.83%
  5. Osteonecrosis Of Jaw (death of bone of jaw): 16 people, 66.67%
  6. Deformity (disfigurement): 15 people, 62.50%
  7. Rashes (redness): 14 people, 58.33%
  8. Dyspnea (difficult or laboured breathing): 14 people, 58.33%
  9. Mucosal Inflammation (infection of mucous membrane): 13 people, 54.17%
  10. High Blood Pressure: 12 people, 50.00%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 5 people, 20.83%
  2. Lung Neoplasm Malignant (cancer tumour of lung): 5 people, 20.83%
  3. Stress And Anxiety: 3 people, 12.50%
  4. Pain: 2 people, 8.33%
  5. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve): 1 person, 4.17%
  6. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 4.17%
  7. Neuralgia (pain in one or more nerves): 1 person, 4.17%
  8. Multiple Myeloma (cancer of the plasma cells): 1 person, 4.17%
  9. Insomnia (sleeplessness): 1 person, 4.17%
  10. Hiv Infection: 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Metformin and have Bone neoplasm malignant?

- Check whether Bone neoplasm malignant is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Metformin:

Bone neoplasm malignant treatments and more:

How severe was Bone neoplasm malignant and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bone neoplasm malignant:

Browse all the conditions that are associated with Bone neoplasm malignant:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Metformin) and Metformin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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