Nolvadex and Vaginal bleeding between periods - a phase IV clinical study of FDA data

Summary:

Vaginal bleeding between periods is reported as a side effect among people who take Nolvadex (tamoxifen citrate), especially for people who are 40-49 old, have been taking the drug for 2 - 5 years also take Arimidex, and have Menopause.

The phase IV clinical study analyzes which people have Vaginal bleeding between periods when taking Nolvadex. It is created by eHealthMe based on reports of 5,421 people who have side effects when taking Nolvadex from the FDA, and is updated regularly.

What is Nolvadex?

Nolvadex has active ingredients of tamoxifen citrate. It is often used in breast cancer. eHealthMe is studying from 5,506 Nolvadex users. Check the latest studies of Nolvadex.

What is Vaginal bleeding between periods?

Vaginal bleeding between periods is found to be associated with 576 drugs and 1,468 conditions by eHealthMe. Check the latest studies of Vaginal bleeding between periods.



On Jul, 23, 2026

5,421 people reported to have side effects when taking Nolvadex.
Among them, 32 people (0.59%) have Vaginal bleeding between periods.

Could Nolvadex cause Vaginal bleeding between periods?

Among these 32 people:

How long have people been on Nolvadex when they have Vaginal bleeding between periods? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 26.67 %
  • 6 - 12 months: 6.67 %
  • 1 - 2 years: 33.33 %
  • 2 - 5 years: 33.33 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Vaginal bleeding between periods when taking Nolvadex? *

  • 0-1: 3.33 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.33 %
  • 40-49: 56.67 %
  • 50-59: 10.0 %
  • 60+: 26.67 %

What are other drugs people take besides Nolvadex? *

  1. Arimidex: 15 people, 46.88%
  2. Leuprolide Acetate: 4 people, 12.50%
  3. Aromasin: 3 people, 9.38%
  4. Zoladex: 3 people, 9.38%
  5. Tenormin: 2 people, 6.25%
  6. Tamoxifen Citrate: 1 person, 3.12%
  7. Synthroid: 1 person, 3.12%
  8. Requip: 1 person, 3.12%
  9. Reclast: 1 person, 3.12%
  10. Perjeta: 1 person, 3.12%

What are other side effects people have besides Vaginal bleeding between periods? *

  1. Uterine Polyp (a mass in the inner lining of the uterus): 9 people, 28.12%
  2. Hot Flush (sudden feelings of heat): 9 people, 28.12%
  3. Weight Increased: 8 people, 25.00%
  4. Nasopharyngitis (inflammation of the nasopharynx): 7 people, 21.88%
  5. Cough: 7 people, 21.88%
  6. Fever: 7 people, 21.88%
  7. Heat Illness: 7 people, 21.88%
  8. High Blood Cholesterol: 7 people, 21.88%
  9. Hyperhidrosis (abnormally increased sweating): 7 people, 21.88%
  10. Injection Site Pain: 7 people, 21.88%

What are the existing conditions these people have? *

  1. Menopause (end of monthly cycles in women): 7 people, 21.88%
  2. Breast Cancer Recurrent: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Nolvadex and have Vaginal bleeding between periods?

- Check whether Vaginal bleeding between periods is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Nolvadex:

Vaginal bleeding between periods treatments and more:

How severe was Vaginal bleeding between periods and when was it recovered:

Expand to all the drugs that have ingredients of tamoxifen citrate:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Nolvadex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Vaginal bleeding between periods:

Browse all the conditions that are associated with Vaginal bleeding between periods:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on tamoxifen citrate (the active ingredients of Nolvadex) and Nolvadex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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