Valium and Flat affect - a phase IV clinical study of FDA data

Summary:

Flat affect is reported as a side effect among people who take Valium (diazepam), especially for people who are female, 50-59 old, also take Oxycontin, and have Pain.

The phase IV clinical study analyzes which people have Flat affect when taking Valium. It is created by eHealthMe based on reports of 45,658 people who have side effects when taking Valium from the FDA, and is updated regularly.

What is Valium?

Valium has active ingredients of diazepam. It is often used in stress and anxiety. eHealthMe is studying from 48,647 Valium users. Check the latest studies of Valium.

What is Flat affect?

Flat affect (absence of emotional response to a situation) is found to be associated with 305 drugs and 454 conditions by eHealthMe. Check the latest studies of Flat affect.

On Jan, 27, 2026

45,658 people reported to have side effects when taking Valium.
Among them, 43 people (0.09%) have Flat affect.

Among these 43 people:

What is the gender of people who have Flat affect when taking Valium? *

female: 58.14 %
male: 41.86 %

What is the age of people who have Flat affect when taking Valium? *

What are other drugs people take besides Valium? *

What are other side effects people have besides Flat affect? *

Depression: 32 people, 74.42%
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 30 people, 69.77%
Weakness: 28 people, 65.12%
Drug Dependence: 28 people, 65.12%
Pain In Extremity: 26 people, 60.47%
Pain: 24 people, 55.81%
Nausea (feeling of having an urge to vomit): 22 people, 51.16%
Chills (felling of cold): 22 people, 51.16%
Joint Pain: 22 people, 51.16%
Fall: 21 people, 48.84%

What are the existing conditions these people have? *

Pain: 24 people, 55.81%
Depression: 3 people, 6.98%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 2.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 2.33%
Panic Disorder: 1 person, 2.33%
Movement - Uncontrolled Or Slow: 1 person, 2.33%
Irritable Bowel Syndrome: 1 person, 2.33%
Impaired Gastric Emptying: 1 person, 2.33%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 2.33%
Gastric Disorder (disease of stomach): 1 person, 2.33%

* Approximation only. Some reports may have incomplete information.

Do you take Valium and have Flat affect?

- Check whether Flat affect is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Valium:

Valium (48,647 reports)

Flat affect treatments and more:

Flat affect (2,784 reports)

Browse all side effects of Valium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flat affect:

Flat affect (305 drugs)

Browse all the conditions that are associated with Flat affect:

Flat affect (454 conditions)

Drugs similar to Valium and Flat affect :

How the study uses the data?

The study uses data from the FDA. It is based on diazepam (the active ingredients of Valium) and Valium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.