Lansoprazole and Sovaldi drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Lansoprazole (lansoprazole) and Sovaldi (sofosbuvir). Common drug interactions include anaemia among females and hepatocellular carcinoma among males.
The phase IV clinical study analyzes what interactions people have when they take Lansoprazole and Sovaldi. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.
What is Lansoprazole?
Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.
What is Sovaldi?
Sovaldi has active ingredients of sofosbuvir. eHealthMe is studying from 12,697 Sovaldi users. Check the latest studies of Sovaldi.
65 people who take Lansoprazole and Sovaldi together, and have interactions are studied.

What are the common drug interactions of Lansoprazole and Sovaldi, by gender? *:
female:
- Anaemia (lack of blood)
- Ataxia (loss of full control of bodily movements)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cardiac failure congestive
- Dyspnoea (difficult or laboured respiration)
- Hyperthyroidism (over activity of the thyroid gland)
- Mitral valve incompetence (inefficient heart valve)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Arthralgia (joint pain)
- Balance disorder
male:
- Hepatocellular carcinoma (liver cancer)
- Renal impairment (severely reduced kidney function)
- Bradycardia (abnormally slow heart action)
- Dizziness
- Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
- Pyrexia (fever)
- Rash
- Sinus node dysfunction (a group of abnormal heart rhythms)
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
What are the common drug interactions of Lansoprazole and Sovaldi, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Hepatic vein thrombosis (obstruction in the veins of the liver caused by a blood clot)
- Hepatocellular carcinoma (liver cancer)
- Hepatic neoplasm (liver tumour)
- Thrombosis (formation of a blood clot inside a blood vessel)
40-49:
- Hepatic neoplasm (liver tumour)
- Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Psychotic disorder
- Death
50-59:
- Anaphylactic reaction (serious allergic reaction)
- Arthralgia (joint pain)
- Ataxia (loss of full control of bodily movements)
- Chest pain
- Cold sweat
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Hepatitis c
- Pyrexia (fever)
- Rash
60+:
- Hepatic encephalopathy (spectrum of neuropsychiatric abnormalities in patients with liver failure)
- Hypertransaminasaemia
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Bone density decreased
- Bone pain
- Cardiac failure congestive
- Cytomegalovirus infection
- Emotional distress
- Gait disturbance
- Hepatocellular carcinoma (liver cancer)
What are the existing conditions these people have? *
- Hepatitis C: 24 people, 36.92%
- Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 14 people, 21.54%
- High Blood Pressure: 7 people, 10.77%
- Diabetes: 7 people, 10.77%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 4 people, 6.15%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 4 people, 6.15%
* Approximation only. Some reports may have incomplete information.
Do you take Lansoprazole and Sovaldi?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Lansoprazole (129,663 reports)
- Sovaldi (12,697 reports)
Browse all drug interactions of Lansoprazole and Sovaldi:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Lansoprazole:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Sovaldi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lansoprazole and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sovaldi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lansoprazole and sofosbuvir (the active ingredients of Lansoprazole and Sovaldi, respectively), and Lansoprazole and Sovaldi (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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