Lymecycline and Epiduo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lymecycline (lymecycline) and Epiduo (adapalene; benzoyl peroxide). Common drug interactions include hyperthermia among females and uveitis among males.

The phase IV clinical study analyzes what interactions people have when they take Lymecycline and Epiduo. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Lymecycline?

Lymecycline has active ingredients of lymecycline. It is often used in acne. eHealthMe is studying from 941 Lymecycline users. Check the latest studies of Lymecycline.

What is Epiduo?

Epiduo has active ingredients of adapalene; benzoyl peroxide. It is often used in acne. eHealthMe is studying from 1,581 Epiduo users. Check the latest studies of Epiduo.

On Jul, 26, 2026

25 people who take Lymecycline and Epiduo together, and have interactions are studied.

Lymecycline and Epiduo drug interactions.

What are the common drug interactions of Lymecycline and Epiduo, by gender? *:

female:

Hyperthermia (body temperature greatly above normal)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Pruritus (severe itching of the skin)
Rash
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Skin burning sensation
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Application site rash
Application site swelling

male:

Uveitis (inflammation of the uvea)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)

What are the common drug interactions of Lymecycline and Epiduo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Chest pain
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Eye swelling
Fatigue (feeling of tiredness)
Headache (pain in head)
Pruritus (severe itching of the skin)
Rash erythematous (redness of the skin)
Skin burning sensation
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

Agitation (state of anxiety or nervous excitement)
Anxiety
Diarrhoea
Hyperreflexia (overactive or over responsive reflexes)
Hyperthermia (body temperature greatly above normal)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Application site rash
Application site swelling

30-39:

Swelling face
Uveitis (inflammation of the uvea)
Depilation (hairlessness)
Rash
Skin exfoliation (removal of the oldest dead skin cells)
Depression
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)

40-49:

Dry skin
Hypersensitivity
Pigmentation disorder (disturbances of human skin colour)
Pruritus (severe itching of the skin)
Rash
Skin burning sensation
Skin discomfort (skin pain/irritation)
Swelling face

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Ill-Defined Disorder: 5 people, 20.00%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 12.00%
Rashes (redness): 2 people, 8.00%
Nausea (feeling of having an urge to vomit): 2 people, 8.00%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 8.00%
Indigestion: 2 people, 8.00%
Fever: 2 people, 8.00%
Depression: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

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