Soolantra and Profen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Soolantra (ivermectin) and Profen (ibuprofen). Common drug interactions include hyperhidrosis among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Soolantra and Profen. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Soolantra?

Soolantra has active ingredients of ivermectin. eHealthMe is studying from 1,068 Soolantra users. Check the latest studies of Soolantra.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

On Jul, 19, 2026

37 people who take Soolantra and Profen together, and have interactions are studied.

What are the common drug interactions of Soolantra and Profen, by gender? *:

female:

Hyperhidrosis (abnormally increased sweating)
Hypokalaemia (low potassium)
Injection site pain
Limb injury
Muscular weakness (muscle weakness)
Oxygen saturation decreased
Rash papular (redness with papule)
Rash pruritic (redness with itching)
Rash pustular (redness with pustules)
Restlessness (not able to rest)

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Exposure to toxic agent
Infusion site discomfort
Infusion site mass
Infusion site pain
Infusion site pruritus (severe itching at infusion site)
Injection site mass
Injection site pain
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Migraine (headache)

What are the common drug interactions of Soolantra and Profen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Injection site pain
Rash pruritic (redness with itching)

40-49:

Erythema (redness of the skin)
Pain of skin
Rash macular (small, flat red spots)
Skin burning sensation
Discomfort
Eye pain
Frequent bowel movements
Hyperhidrosis (abnormally increased sweating)
Restlessness (not able to rest)
Fatigue (feeling of tiredness)

50-59:

Arthralgia (joint pain)
Nausea (feeling of having an urge to vomit)
Cervical cyst (mucus-filled cyst on the surface of the cervix)
Diarrhoea
Dry skin
Flatulence (flatus expelled through the anus)
Leukopenia (less number of white blood cells in blood)
Mucosal dryness (dryness of mucous membrane)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)

60+:

Chronic kidney disease
Death
Rosacea (a skin condition that causes facial redness)
Skin irritation
Syncope (loss of consciousness with an inability to maintain postural tone)
Tendonitis (a condition that causes pain and swelling of tendons)
Toothache (tooth pain)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Dermatitis allergic (inflammation of the skin due allergic reaction)
Erythema (redness of the skin)

What are the existing conditions these people have? *

Fibromyalgia (a long-term condition which causes pain all over the body): 13 people, 35.14%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 13.51%
Rosacea (a skin condition that causes facial redness): 5 people, 13.51%
Depression: 4 people, 10.81%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 10.81%
Stress And Anxiety: 4 people, 10.81%
Constipation: 3 people, 8.11%
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus): 3 people, 8.11%
Dyspnea (difficult or laboured breathing): 3 people, 8.11%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 3 people, 8.11%

* Approximation only. Some reports may have incomplete information.

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