Zopiclone and Tarceva drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Zopiclone (eszopiclone) and Tarceva (erlotinib hydrochloride). Common drug interactions include diarrhoea among females and death among males.
The phase IV clinical study analyzes what interactions people have when they take Zopiclone and Tarceva. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Zopiclone?
Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. eHealthMe is studying from 54,330 Zopiclone users. Check the latest studies of Zopiclone.
What is Tarceva?
Tarceva has active ingredients of erlotinib hydrochloride. It is often used in lung cancer. eHealthMe is studying from 31,036 Tarceva users. Check the latest studies of Tarceva.
12 people who take Zopiclone and Tarceva together, and have interactions are studied.

What are the common drug interactions of Zopiclone and Tarceva, by gender? *:
female:
- Diarrhoea
- Neutropenia (an abnormally low number of neutrophils)
- Abdominal discomfort
- Anaphylactic reaction (serious allergic reaction)
- Back pain
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Cellulitis (infection under the skin)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Cough
- Disease progression
male:
- Death
- Lung disorder (lung disease)
- Dyspepsia (indigestion)
- Fungal infection
- Gait disturbance
- General physical health deterioration (weak health status)
- Hepatic enzyme increased
- Hypokinesia (decreased bodily movement)
- Hypoxia (low oxygen in tissues)
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
What are the common drug interactions of Zopiclone and Tarceva, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anaphylactic reaction (serious allergic reaction)
- Back pain
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Cellulitis (infection under the skin)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Diarrhoea
- Disease progression
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Electrocardiogram st segment elevation
50-59:
n/a
60+:
- Death
- Lung disorder (lung disease)
- Fungal infection
- General physical health deterioration (weak health status)
- Hypokinesia (decreased bodily movement)
- Hypoxia (low oxygen in tissues)
- Malignant neoplasm progression (cancer tumour came back)
- Pain
- Pneumonia pneumococcal (pneumococcal pneumonia is a common but serious infection and inflammation of the lungs)
- Prostatic specific antigen increased
What are the existing conditions these people have? *
- Lung Neoplasm Malignant (cancer tumour of lung): 4 people, 33.33%
- Metastases To Bone (cancer spreads to bone): 3 people, 25.00%
- Pain: 2 people, 16.67%
- Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 2 people, 16.67%
- Lung Cancer - Non-Small Cell (lung cancer): 2 people, 16.67%
- Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins): 2 people, 16.67%
- Stress And Anxiety: 1 person, 8.33%
- Prostate Cancer Metastatic: 1 person, 8.33%
- Prostate Cancer: 1 person, 8.33%
- Pancreatic Carcinoma Metastatic (pancreatic cancer- metastatic): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Zopiclone and Tarceva?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Zopiclone and Tarceva:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Zopiclone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Tarceva:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zopiclone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Tarceva and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
- Lai SW, Lai HC, Lin CL, Liao KF, "Zopiclone use associated with increased risk of acute pancreatitis: a case–control study in Taiwan", International journal of clinical practice, 2015 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on eszopiclone and erlotinib hydrochloride (the active ingredients of Zopiclone and Tarceva, respectively), and Zopiclone and Tarceva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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