A study for a 66 year old man who takes Wellbutrin Sr, Eliquis, Loratadine, Montelukast Sodium, Coreg (an AI-powered real world drug study)
Summary:
12 males aged 66 (±5) who take the same drugs and have adverse effects are studied. This is a phase IV clinical study for a 66 year old male patient who has Depression, Allergic Reactions, High Blood Pressure, Wheezing, A-Fib. The study is created by eHealthMe based on reports from sources including the FDA.
12 males aged 66 (±5) who take Wellbutrin Sr, Eliquis, Loratadine, Montelukast Sodium, Coreg and have adverse effects are studied.
Number of reports submitted per year:

Information of the patient in this study:
- Age: 66
- Gender: male
What are the drugs?
- Wellbutrin sr has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 13,112 Wellbutrin sr users. Check the latest studies of Wellbutrin sr.
- Eliquis has active ingredients of apixaban. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 191,861 Eliquis users. Check the latest studies of Eliquis.
- Loratadine has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 56,314 Loratadine users. Check the latest studies of Loratadine.
- Montelukast sodium has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 26,094 Montelukast sodium users. Check the latest studies of Montelukast sodium.
- Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.
What are the conditions?
- Depression is found to be associated with 3,169 drugs and 4,129 conditions by eHealthMe. Check the latest studies of Depression.
- Allergic reactions is found to be associated with 19 drugs and 167 conditions by eHealthMe. Check the latest studies of Allergic reactions.
- High blood pressure is found to be associated with 3,482 drugs and 5,247 conditions by eHealthMe. Check the latest studies of High blood pressure.
- Wheezing (a high-pitched whistling sound made while you breath) is found to be associated with 1,799 drugs and 2,209 conditions by eHealthMe. Check the latest studies of Wheezing.
- A-fib (most common type of arrhythmia) is found to be associated with 2,868 drugs and 3,843 conditions by eHealthMe. Check the latest studies of A-fib.
What are the adverse effects?
- A-fib (most common type of arrhythmia) is found to be associated with 2,868 drugs and 3,843 conditions by eHealthMe. Check the latest studies of A-fib.
- Allergies is found to be associated with 2 drugs and 87 conditions by eHealthMe. Check the latest studies of Allergies.
- Asthma is found to be associated with 2,097 drugs and 2,614 conditions by eHealthMe. Check the latest studies of Asthma.
- Wheezing (a high-pitched whistling sound made while you breath) is found to be associated with 1,799 drugs and 2,209 conditions by eHealthMe. Check the latest studies of Wheezing.
- Depression is found to be associated with 3,169 drugs and 4,129 conditions by eHealthMe. Check the latest studies of Depression.
Comparison with patient's specific adverse outcomes:
You can check what is more associated with an adverse outcome: a drug mix, a drug, a condition, or a population of certain gender and age. Each patient is different. It is not uncommon that the results can be inconclusive or insignificant.
By the same drug(s):
-
A-Fib (most common type of arrhythmia):
- among males aged 66 (±5) who take the same drugs: 0% (0 of 12)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 127) -
Allergies:
- among males aged 66 (±5) who take the same drugs: 0% (0 of 12)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 127) -
Asthma:
- among males aged 66 (±5) who take the same drugs: 0% (0 of 12)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 127) -
Wheezing (a high-pitched whistling sound made while you breath):
- among males aged 66 (±5) who take the same drugs: 0% (0 of 12)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 127) -
Depression:
- among males aged 66 (±5) who take the same drugs: 0% (0 of 12)
- among people who take the same drugs, regardless of gender or age: 0% (0 of 127)
By each condition:
-
people who have A-Fib with Depression:
- among males aged 66 (±5) who have Depression: 1.39% (203 of 14,555)
- among people who have Depression, regardless of gender or age: 0.52% (1,791 of 344,182) -
people who have A-Fib with Allergic Reactions:
- among males aged 66 (±5) who have Allergic Reactions: 1.76% (7 of 397)
- among people who have Allergic Reactions, regardless of gender or age: 0.8% (30 of 3,731) -
people who have A-Fib with Wheezing:
- among males aged 66 (±5) who have Wheezing: 2.28% (17 of 744)
- among people who have Wheezing, regardless of gender or age: 1.82% (191 of 10,478) -
people who have A-Fib with High Blood Pressure:
- among males aged 66 (±5) who have High Blood Pressure: 1.76% (1,215 of 69,222)
- among people who have High Blood Pressure, regardless of gender or age: 1.42% (8,570 of 605,312) -
people who have Allergies with A-Fib:
- among males aged 66 (±5) who have A-Fib: 0% (0 of 28,880)
- among people who have A-Fib, regardless of gender or age: 0% (0 of 226,254) -
people who have Allergies with High Blood Pressure:
- among males aged 66 (±5) who have High Blood Pressure: 0% (0 of 69,222)
- among people who have High Blood Pressure, regardless of gender or age: 0% (1 of 605,312) -
people who have Allergies with Wheezing:
- among males aged 66 (±5) who have Wheezing: 0% (0 of 744)
- among people who have Wheezing, regardless of gender or age: 0% (0 of 10,478) -
people who have Allergies with Allergic Reactions:
- among males aged 66 (±5) who have Allergic Reactions: 0% (0 of 397)
- among people who have Allergic Reactions, regardless of gender or age: 0% (0 of 3,731) -
people who have Allergies with Depression:
- among males aged 66 (±5) who have Depression: 0% (0 of 14,555)
- among people who have Depression, regardless of gender or age: 0% (0 of 344,182) -
people who have Asthma with Allergic Reactions:
- among males aged 66 (±5) who have Allergic Reactions: 1.01% (4 of 397)
- among people who have Allergic Reactions, regardless of gender or age: 0.86% (32 of 3,731) -
people who have Asthma with High Blood Pressure:
- among males aged 66 (±5) who have High Blood Pressure: 0.48% (334 of 69,222)
- among people who have High Blood Pressure, regardless of gender or age: 0.72% (4,354 of 605,312) -
people who have Asthma with Depression:
- among males aged 66 (±5) who have Depression: 0.3% (44 of 14,555)
- among people who have Depression, regardless of gender or age: 0.61% (2,114 of 344,182) -
people who have Asthma with Wheezing:
- among males aged 66 (±5) who have Wheezing: 11.16% (83 of 744)
- among people who have Wheezing, regardless of gender or age: 7.59% (795 of 10,478) -
people who have Asthma with A-Fib:
- among males aged 66 (±5) who have A-Fib: 0.13% (38 of 28,880)
- among people who have A-Fib, regardless of gender or age: 0.16% (373 of 226,254) -
people who have Depression with Allergic Reactions:
- among males aged 66 (±5) who have Allergic Reactions: 0% (0 of 397)
- among people who have Allergic Reactions, regardless of gender or age: 0.29% (11 of 3,731) -
people who have Depression with A-Fib:
- among males aged 66 (±5) who have A-Fib: 0.38% (111 of 28,880)
- among people who have A-Fib, regardless of gender or age: 0.51% (1,156 of 226,254) -
people who have Depression with Wheezing:
- among males aged 66 (±5) who have Wheezing: 1.34% (10 of 744)
- among people who have Wheezing, regardless of gender or age: 1.8% (189 of 10,478) -
people who have Depression with High Blood Pressure:
- among males aged 66 (±5) who have High Blood Pressure: 1.07% (742 of 69,222)
- among people who have High Blood Pressure, regardless of gender or age: 1.83% (11,075 of 605,312) -
people who have Wheezing with A-Fib:
- among males aged 66 (±5) who have A-Fib: 0.21% (62 of 28,880)
- among people who have A-Fib, regardless of gender or age: 0.42% (950 of 226,254) -
people who have Wheezing with Depression:
- among males aged 66 (±5) who have Depression: 0.29% (42 of 14,555)
- among people who have Depression, regardless of gender or age: 0.31% (1,054 of 344,182) -
people who have Wheezing with Allergic Reactions:
- among males aged 66 (±5) who have Allergic Reactions: 0% (0 of 397)
- among people who have Allergic Reactions, regardless of gender or age: 0.78% (29 of 3,731) -
people who have Wheezing with High Blood Pressure:
- among males aged 66 (±5) who have High Blood Pressure: 0.42% (291 of 69,222)
- among people who have High Blood Pressure, regardless of gender or age: 0.47% (2,875 of 605,312)
By each drug (FDA data only):
-
people who take Wellbutrin Sr and have A-Fib:
- among males aged 66 (±5) who take Wellbutrin Sr and have side effects: 0.81% (2 of 247)
- among people who take Wellbutrin Sr and have side effects, regardless of gender or age: 0.38% (36 of 9,392) -
people who take Loratadine and have A-Fib:
- among males aged 66 (±5) who take Loratadine and have side effects: 1.76% (62 of 3,513)
- among people who take Loratadine and have side effects, regardless of gender or age: 1.07% (576 of 54,001) -
people who take Montelukast Sodium and have A-Fib:
- among males aged 66 (±5) who take Montelukast Sodium and have side effects: 1.58% (20 of 1,265)
- among people who take Montelukast Sodium and have side effects, regardless of gender or age: 1.08% (268 of 24,782) -
people who take Eliquis and have A-Fib:
- among males aged 66 (±5) who take Eliquis and have side effects: 5.28% (751 of 14,229)
- among people who take Eliquis and have side effects, regardless of gender or age: 3.77% (7,141 of 189,426) -
people who take Coreg and have A-Fib:
- among males aged 66 (±5) who take Coreg and have side effects: 4.78% (283 of 5,925)
- among people who take Coreg and have side effects, regardless of gender or age: 3.59% (1,730 of 48,178) -
people who take Loratadine and have Allergies:
- among males aged 66 (±5) who take Loratadine and have side effects: 0% (0 of 3,513)
- among people who take Loratadine and have side effects, regardless of gender or age: 0% (0 of 54,001) -
people who take Eliquis and have Allergies:
- among males aged 66 (±5) who take Eliquis and have side effects: 0% (0 of 14,229)
- among people who take Eliquis and have side effects, regardless of gender or age: 0% (0 of 189,426) -
people who take Coreg and have Allergies:
- among males aged 66 (±5) who take Coreg and have side effects: 0% (0 of 5,925)
- among people who take Coreg and have side effects, regardless of gender or age: 0% (0 of 48,178) -
people who take Wellbutrin Sr and have Allergies:
- among males aged 66 (±5) who take Wellbutrin Sr and have side effects: 0% (0 of 247)
- among people who take Wellbutrin Sr and have side effects, regardless of gender or age: 0% (0 of 9,392) -
people who take Montelukast Sodium and have Allergies:
- among males aged 66 (±5) who take Montelukast Sodium and have side effects: 0% (0 of 1,265)
- among people who take Montelukast Sodium and have side effects, regardless of gender or age: 0% (0 of 24,782) -
people who take Wellbutrin Sr and have Asthma:
- among males aged 66 (±5) who take Wellbutrin Sr and have side effects: 0.4% (1 of 247)
- among people who take Wellbutrin Sr and have side effects, regardless of gender or age: 1.06% (100 of 9,392) -
people who take Coreg and have Asthma:
- among males aged 66 (±5) who take Coreg and have side effects: 0.34% (20 of 5,925)
- among people who take Coreg and have side effects, regardless of gender or age: 0.73% (351 of 48,178) -
people who take Eliquis and have Asthma:
- among males aged 66 (±5) who take Eliquis and have side effects: 0.9% (128 of 14,229)
- among people who take Eliquis and have side effects, regardless of gender or age: 0.68% (1,285 of 189,426) -
people who take Loratadine and have Asthma:
- among males aged 66 (±5) who take Loratadine and have side effects: 0.71% (25 of 3,513)
- among people who take Loratadine and have side effects, regardless of gender or age: 1.71% (922 of 54,001) -
people who take Montelukast Sodium and have Asthma:
- among males aged 66 (±5) who take Montelukast Sodium and have side effects: 21.74% (275 of 1,265)
- among people who take Montelukast Sodium and have side effects, regardless of gender or age: 14.25% (3,532 of 24,782) -
people who take Wellbutrin Sr and have Depression:
- among males aged 66 (±5) who take Wellbutrin Sr and have side effects: 6.07% (15 of 247)
- among people who take Wellbutrin Sr and have side effects, regardless of gender or age: 7.45% (700 of 9,392) -
people who take Eliquis and have Depression:
- among males aged 66 (±5) who take Eliquis and have side effects: 0.48% (69 of 14,229)
- among people who take Eliquis and have side effects, regardless of gender or age: 0.62% (1,165 of 189,426) -
people who take Montelukast Sodium and have Depression:
- among males aged 66 (±5) who take Montelukast Sodium and have side effects: 1.74% (22 of 1,265)
- among people who take Montelukast Sodium and have side effects, regardless of gender or age: 3.51% (871 of 24,782) -
people who take Loratadine and have Depression:
- among males aged 66 (±5) who take Loratadine and have side effects: 1.74% (61 of 3,513)
- among people who take Loratadine and have side effects, regardless of gender or age: 2.78% (1,502 of 54,001) -
people who take Coreg and have Depression:
- among males aged 66 (±5) who take Coreg and have side effects: 1.96% (116 of 5,925)
- among people who take Coreg and have side effects, regardless of gender or age: 2.59% (1,246 of 48,178) -
people who take Montelukast Sodium and have Wheezing:
- among males aged 66 (±5) who take Montelukast Sodium and have side effects: 14.55% (184 of 1,265)
- among people who take Montelukast Sodium and have side effects, regardless of gender or age: 6.92% (1,716 of 24,782) -
people who take Eliquis and have Wheezing:
- among males aged 66 (±5) who take Eliquis and have side effects: 0.42% (60 of 14,229)
- among people who take Eliquis and have side effects, regardless of gender or age: 0.59% (1,122 of 189,426) -
people who take Coreg and have Wheezing:
- among males aged 66 (±5) who take Coreg and have side effects: 0.51% (30 of 5,925)
- among people who take Coreg and have side effects, regardless of gender or age: 0.61% (295 of 48,178) -
people who take Wellbutrin Sr and have Wheezing:
- among males aged 66 (±5) who take Wellbutrin Sr and have side effects: 0% (0 of 247)
- among people who take Wellbutrin Sr and have side effects, regardless of gender or age: 0.47% (44 of 9,392) -
people who take Loratadine and have Wheezing:
- among males aged 66 (±5) who take Loratadine and have side effects: 0.37% (13 of 3,513)
- among people who take Loratadine and have side effects, regardless of gender or age: 0.8% (432 of 54,001)
Common drug interactions *:
- Fever : 3 people, 25.00%
- Ventricular Tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart): 2 people, 16.67%
- Death : 2 people, 16.67%
- Heart Rate Decreased : 2 people, 16.67%
- Disability : 1 person, 8.33%
- General Physical Health Deterioration (weak health status): 1 person, 8.33%
- Eating Disorder : 1 person, 8.33%
- Dyspnea (difficult or laboured breathing): 1 person, 8.33%
- Drug Dependence : 1 person, 8.33%
- Drowsiness : 1 person, 8.33%
- Disease Progression : 1 person, 8.33%
- Weakness : 1 person, 8.33%
- Constipation : 1 person, 8.33%
- Cardiac Failure Congestive : 1 person, 8.33%
- Body Temperature Increased : 1 person, 8.33%
- Bedwetting : 1 person, 8.33%
- Arthritis Infective (purulent invasion of a joint by an infectious agent which produces arthritis): 1 person, 8.33%
- Apathy : 1 person, 8.33%
- Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 1 person, 8.33%
- Dehydration (dryness resulting from the removal of water): 1 person, 8.33%
Common co-existing conditions *:
You may use this to check any potential undetected conditions.
- Multiple Myeloma (cancer of the plasma cells): 3 people, 25.00%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 16.67%
- Gout (uric acid crystals building up in the body): 1 person, 8.33%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 8.33%
- Gait Disturbance : 1 person, 8.33%
- Enlarged Prostate : 1 person, 8.33%
- Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 8.33%
Common co-used drugs *:
You may use this to check any potential interacting drugs.
- Tamsulosin (5 people, 41.67%)
- Metformin (4 people, 33.33%)
- Pantoprazole (4 people, 33.33%)
- Divalproex (3 people, 25.00%)
- Amlodipine (3 people, 25.00%)
- Protonix (3 people, 25.00%)
- Ibrutinib (3 people, 25.00%)
- Entresto (2 people, 16.67%)
- Farxiga (2 people, 16.67%)
- Fish Oil (2 people, 16.67%)
- Spironolactone (2 people, 16.67%)
- Calcium (2 people, 16.67%)
- Levemir (2 people, 16.67%)
- Ranexa (2 people, 16.67%)
- Aspirin (2 people, 16.67%)
- Miralax (2 people, 16.67%)
- Ezetimibe (2 people, 16.67%)
- Vitamin C (2 people, 16.67%)
- Vitamin D (2 people, 16.67%)
- Ampyra (2 people, 16.67%)
Drug effectiveness *:
Wellbutrin Sr:
n/a
Eliquis:
n/a
Loratadine:
n/a
Montelukast Sodium:
n/a
Coreg:
n/a
* Some reports may have incomplete information.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Related studies
Drug side effects in long term, by gender and age:
- Coreg: 49,583 reports
- Eliquis: 191,861 reports
- Loratadine: 56,314 reports
- Montelukast sodium: 26,094 reports
- Wellbutrin sr: 13,112 reports
Treatments, associated medications and conditions:
- A-fib: 349,230 reports
- Allergic reactions: 15,371 reports
- Allergies: 15,371 reports
- Asthma: 354,187 reports
- Depression: 652,152 reports
- High blood pressure: 1,062,858 reports
- Wheezing: 77,220 reports
Drug side effects:
- Wellbutrin sr and A-fib (36 reports)
- Eliquis and A-fib (7,141 reports)
- Loratadine and A-fib (578 reports)
- Montelukast sodium and A-fib (268 reports)
- Coreg and A-fib (1,730 reports)
- Wellbutrin sr and Allergies
- Eliquis and Allergies
- Loratadine and Allergies
- Montelukast sodium and Allergies
- Coreg and Allergies
- Wellbutrin sr and Asthma (100 reports)
- Eliquis and Asthma (1,285 reports)
- Loratadine and Asthma (922 reports)
- Montelukast sodium and Asthma (3,532 reports)
- Coreg and Asthma (342 reports)
- Wellbutrin sr and Wheezing (44 reports)
- Eliquis and Wheezing (1,122 reports)
- Loratadine and Wheezing (432 reports)
- Montelukast sodium and Wheezing (1,716 reports)
- Coreg and Wheezing (295 reports)
- Wellbutrin sr and Depression (700 reports)
- Eliquis and Depression (1,165 reports)
- Loratadine and Depression (1,486 reports)
- Montelukast sodium and Depression (871 reports)
- Coreg and Depression (1,246 reports)
Drug interactions:
- Wellbutrin sr and Eliquis drug interaction (52 reports)
- Wellbutrin sr and Loratadine drug interaction (97 reports)
- Wellbutrin sr and Montelukast sodium drug interaction (63 reports)
- Wellbutrin sr and Coreg drug interaction (96 reports)
- Eliquis and Loratadine drug interaction (1,180 reports)
- Eliquis and Montelukast sodium drug interaction (833 reports)
- Eliquis and Coreg drug interaction (1,601 reports)
- Loratadine and Montelukast sodium drug interaction (1,202 reports)
- Loratadine and Coreg drug interaction (525 reports)
- Montelukast sodium and Coreg drug interaction (129 reports)
Symptoms:
- Depression and Allergies
- Depression and Asthma (2,100 reports)
- Depression and Wheezing (1,054 reports)
- Depression and Depression (17,292 reports)
- Allergic reactions and Allergies (14 reports)
- Allergic reactions and Asthma (32 reports)
- Allergic reactions and Wheezing (27 reports)
- Allergic reactions and Depression (11 reports)
- High blood pressure and Allergies (1 reports)
- High blood pressure and Asthma (4,354 reports)
- High blood pressure and Wheezing (2,875 reports)
- High blood pressure and Depression (11,075 reports)
- Wheezing and Allergies
- Wheezing and Asthma (793 reports)
- Wheezing and Wheezing (275 reports)
- Wheezing and Depression (189 reports)
- A-fib and Allergies
- A-fib and Asthma (370 reports)
- A-fib and Wheezing (950 reports)
- A-fib and Depression (1,156 reports)
Drugs that are associated with:
- A-fib: 2,868 drugs
- Allergies: 2 drugs
- Asthma: 2,097 drugs
- Wheezing: 1,799 drugs
- Depression: 3,169 drugs
Conditions that are associated with:
- A-fib: 3,843 conditions
- Allergies: 87 conditions
- Asthma: 2,614 conditions
- Wheezing: 2,209 conditions
- Depression: 4,129 conditions
How the phase IV clinical study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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