Cisplatin and Wellbutrin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cisplatin (cisplatin) and Wellbutrin (bupropion hydrochloride). Common drug interactions include hypokalaemia among females and dehydration among males.
The phase IV clinical study analyzes what interactions people have when they take Cisplatin and Wellbutrin. It is created by eHealthMe based on reports of 90 people who take the same drugs from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Wellbutrin?
Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. eHealthMe is studying from 117,107 Wellbutrin users. Check the latest studies of Wellbutrin.
90 people who take Cisplatin and Wellbutrin together, and have interactions are studied.

What are the common drug interactions of Cisplatin and Wellbutrin, by gender? *:
female:
- Hypokalaemia (low potassium)
- Local swelling (swelling at the site of some application of substance or injury)
- Pyrexia (fever)
- Urinary tract infection
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthralgia (joint pain)
- Chest pain
- Cough
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
male:
- Dehydration (dryness resulting from the removal of water)
- Dyspnoea (difficult or laboured respiration)
- Nausea (feeling of having an urge to vomit)
- Colitis (inflammation of colon)
- Fall
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Dizziness
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Neoplasm malignant (cancer tumour)
What are the common drug interactions of Cisplatin and Wellbutrin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Implant infection (infection at implant site)
- Vomiting
- Abdominal pain
- Adnexa uteri mass (ovarian cysts)
- Anaemia (lack of blood)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Arthralgia (joint pain)
- Ascites (accumulation of fluid in the abdominal cavity)
- Back pain
- Blood creatine phosphokinase mb increased
40-49:
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Colitis (inflammation of colon)
- Gastritis erosive (a break in the surface layer of the membrane lining the stomach with infection)
- Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
- Hypovolaemia (a decreased volume of circulating blood in the body)
- Pneumonia
- Pulmonary embolism (blockage of the main artery of the lung)
- Febrile neutropenia (fever with reduced white blood cells)
- Nausea (feeling of having an urge to vomit)
50-59:
- Abdominal pain
- Diarrhoea
- Asthenia (weakness)
- Chest pain
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Neutropenia (an abnormally low number of neutrophils)
- Pyrexia (fever)
- Anaemia (lack of blood)
- Dehydration (dryness resulting from the removal of water)
- Hypoaesthesia (reduced sense of touch or sensation)
60+:
- Dyspnoea (difficult or laboured respiration)
- Decreased appetite
- Abdominal pain
- Chest pain
- Neutropenia (an abnormally low number of neutrophils)
- Non-small cell lung cancer metastatic (type of epithelial lung cancer spreads to other parts)
- Urinary tract infection
- Neoplasm progression (growth of tumour)
- Acute stress disorder
- Anaemia (lack of blood)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 16 people, 17.78%
- Oesophageal Carcinoma (cancer tumour of oesophagus): 9 people, 10.00%
- Pain: 8 people, 8.89%
- Nausea (feeling of having an urge to vomit): 8 people, 8.89%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and Wellbutrin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cisplatin (92,837 reports)
- Wellbutrin (117,107 reports)
Browse all drug interactions of Cisplatin and Wellbutrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Wellbutrin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Wellbutrin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin and bupropion hydrochloride (the active ingredients of Cisplatin and Wellbutrin, respectively), and Cisplatin and Wellbutrin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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