Activase and Stroke - a phase IV clinical study of FDA data
Summary:
Stroke is reported as a side effect among people who take Activase (alteplase), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Plavix, and have Ischaemic stroke.
The phase IV clinical study analyzes which people have Stroke when taking Activase. It is created by eHealthMe based on reports of 7,505 people who have side effects when taking Activase from the FDA, and is updated regularly.
What is Activase?
Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.
What is Stroke?
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,365 drugs and 3,015 conditions by eHealthMe. Check the latest studies of Stroke.
7,505 people reported to have side effects when taking Activase.
Among them, 114 people (1.52%) have Stroke.

Among these 114 people:
How long have people been on Activase when they have Stroke? *
What is the gender of people who have Stroke when taking Activase? *
What is the age of people who have Stroke when taking Activase? *
What are other drugs people take besides Activase? *
What are other side effects people have besides Stroke? *
What are the existing conditions these people have? *
* Approximation only. Some reports may have incomplete information.
Do you take Activase and have Stroke?
- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Activase:
- Activase (7,526 reports)
Stroke treatments and more:
- Stroke (334,632 reports)
How severe was Stroke and when was it recovered:
Expand to all the drugs that have ingredients of alteplase:
- Stroke and drugs with ingredients of alteplase (294 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Activase side effects:
- Activase side effect: Death (755 reports)
- Activase side effect: Chest pain (539 reports)
- Activase side effect: Haemorrhage (bleeding) (385 reports)
- Activase side effect: Drug ineffective (324 reports)
- Activase side effect: Haemorrhage intracranial (bleeding within the skull) (321 reports)
Browse all side effects of Activase:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Stroke:
- Vioxx side effect: Stroke (24,895 reports)
- Avandia side effect: Stroke (22,492 reports)
- Aspirin side effect: Stroke (12,887 reports)
- Lipitor side effect: Stroke (6,554 reports)
- Plavix side effect: Stroke (6,381 reports)
- Celebrex side effect: Stroke (5,812 reports)
- Metformin side effect: Stroke (5,698 reports)
- Lisinopril side effect: Stroke (5,666 reports)
- Xarelto side effect: Stroke (5,623 reports)
- Eliquis side effect: Stroke (5,156 reports)
Browse all the drugs that are associated with Stroke:
- Stroke (2,365 drugs)
Common conditions associated with Stroke:
- Diabetes mellitus: 23,761 reports
- Diabetes: 23,701 reports
- Dm: 23,693 reports
- Glucose test: 22,610 reports
- Hypertension: 9,196 reports
- High blood pressure: 9,160 reports
- Blood pressure - high: 9,158 reports
- Ra: 8,151 reports
- Rheumatoid arthritis: 8,097 reports
- Multiple sclerosis: 6,970 reports
Browse all the conditions that are associated with Stroke:
- Stroke (3,015 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on alteplase (the active ingredients of Activase) and Activase (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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