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Complement factor c3 decreased and drugs of ingredients of ibuprofen (a real world drug study)


Summary:

Complement factor c3 decreased is found among people who take drugs with ingredients of ibuprofen, especially for people who are female, 50-59 old , have been taking the drugs for 2 - 5 years. This phase IV clinical study is created by eHealthMe based on reports of 344,432 people who have side effects when taking drugs with ingredients of ibuprofen from the FDA, and is updated regularly.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Aches-n-pain, Advil, Advil liqui-gels, Advil migraine liqui-gels, Caldolor, Cap-profen, Children's advil, Children's advil-flavored, Children's elixsure, Children's ibuprofen, Children's motrin, Ibu, Ibu-tab, Ibu-tab 200, Ibuprin, Ibuprofen, Ibuprohm, Infant's advil, Junior strength advil, Junior strength ibuprofen, Junior strength motrin, Medipren, Midol, Midol liquid gels, Motrin, Motrin ib, Motrin migraine pain, Nuprin, Pediatric advil, Profen, Rufen, Tab-profen.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jun, 05, 2026

344,432 people reported to have side effects when taking drugs with ingredients of ibuprofen.
Among them, 20 people (0.01%) have Complement factor c3 decreased

What is Complement factor c3 decreased?

Complement factor c3 decreased is found to be associated with 49 drugs and 202 conditions by eHealthMe. Check the latest studies of Complement factor c3 decreased.

Number of reports submitted per year:

Could drugs with ingredients of ibuprofen cause Complement factor c3 decreased?

Time on drugs with ingredients of ibuprofen when people have Complement factor c3 decreased *:

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

Gender of people who have Complement factor c3 decreased when taking drugs with ingredients of ibuprofen *:

  • female: 58.82 %
  • male: 41.18 %

Age of people who have Complement factor c3 decreased when taking drugs with ingredients of ibuprofen *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 11.76 %
  • 50-59: 47.06 %
  • 60+: 41.18 %

Conditions people have *:

You may use this to check any potential undetected conditions.

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 45.00%
  2. Sleep Disorder: 6 people, 30.00%
  3. Nasopharyngitis (inflammation of the nasopharynx): 6 people, 30.00%
  4. Upper Respiratory Tract Infection: 1 person, 5.00%
  5. Pathogen Resistance: 1 person, 5.00%
  6. Antinuclear Antibody Positive: 1 person, 5.00%

Other drugs people take *:

You may use this to check any potential interacting drugs.

  1. Prednisone: 10 people, 50.00%
  2. Zopiclone: 9 people, 45.00%
  3. Darifenacin Hydrobromide: 9 people, 45.00%
  4. Enbrel: 9 people, 45.00%
  5. Hydroxychloroquine Sulfate: 9 people, 45.00%
  6. Imitrex: 9 people, 45.00%
  7. Methylprednisolone: 9 people, 45.00%
  8. Pantoprazole: 9 people, 45.00%
  9. Melatonin: 9 people, 45.00%
  10. Acetaminophen: 9 people, 45.00%

Other side effects people have besides Complement factor c3 decreased *:

You may use this to check any potential undetected side effects.

  1. Complement Factor C4 Decreased: 18 people, 90.00%
  2. C-Reactive Protein Increased: 15 people, 75.00%
  3. White Blood Cell Count Increased: 10 people, 50.00%
  4. Urinary Tract Infection: 10 people, 50.00%
  5. Red Blood Cell Count Decreased: 10 people, 50.00%
  6. Neutrophil Count Increased (excess than normal number of neutrophil a type of blood cell): 9 people, 45.00%
  7. Haemoglobin Decreased: 9 people, 45.00%
  8. Lymphocyte Count Decreased: 9 people, 45.00%
  9. Mean Cell Haemoglobin Decreased (less than normal haemoglobin per red blood cell in a sample of blood): 9 people, 45.00%
  10. Granulocyte Count Increased: 9 people, 45.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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