Escitalopram and Sinus node dysfunction - a phase IV clinical study of FDA data

Summary:

Sinus node dysfunction is reported as a side effect among people who take Escitalopram (escitalopram oxalate), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Amlodipine, and have Blood testosterone decreased.

The phase IV clinical study analyzes which people have Sinus node dysfunction when taking Escitalopram. It is created by eHealthMe based on reports of 75,134 people who have side effects when taking Escitalopram from the FDA, and is updated regularly.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,075 Escitalopram users. Check the latest studies of Escitalopram.

What is Sinus node dysfunction?

Sinus node dysfunction (a group of abnormal heart rhythms) is found to be associated with 1,264 drugs and 834 conditions by eHealthMe. Check the latest studies of Sinus node dysfunction.

On Aug, 22, 2025

75,134 people reported to have side effects when taking Escitalopram.
Among them, 15 people (0.02%) have Sinus node dysfunction.

Could Escitalopram cause Sinus node dysfunction?

Among these 15 people:

How long have people been on Escitalopram when they have Sinus node dysfunction? *

What is the gender of people who have Sinus node dysfunction when taking Escitalopram? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Sinus node dysfunction when taking Escitalopram? *

What are other drugs people take besides Escitalopram? *

What are other side effects people have besides Sinus node dysfunction? *

Dizziness: 12 people, 80.00%
Fainting (loss of consciousness and postural tone): 12 people, 80.00%
Withdrawal Syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance): 11 people, 73.33%
Mood Swings (an extreme or rapid change in mood): 11 people, 73.33%
Anaemia (lack of blood): 11 people, 73.33%
Anger: 11 people, 73.33%
Bradycardia (abnormally slow heart action): 11 people, 73.33%
Bruxism (habitual grinding of the teeth, typically during sleep): 11 people, 73.33%
Coordination Abnormal (abnormal movement): 11 people, 73.33%
Dyskinesia (abnormality or impairment of voluntary movement): 11 people, 73.33%

What are the existing conditions these people have? *

Prostatic Disorder: 3 people, 20.00%
High Blood Cholesterol: 3 people, 20.00%
Blood Testosterone Decreased: 3 people, 20.00%
Prostatomegaly (enlargement of the prostate): 2 people, 13.33%
Irritability: 1 person, 6.67%
Insomnia (sleeplessness): 1 person, 6.67%
Indigestion: 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Dementia (madness): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Escitalopram and have Sinus node dysfunction?

- Check whether Sinus node dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Escitalopram:

Escitalopram (78,075 reports)

Browse all side effects of Escitalopram:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Sinus node dysfunction:

Sinus node dysfunction (1,264 drugs)

Browse all the conditions that are associated with Sinus node dysfunction:

Sinus node dysfunction (834 conditions)

Drugs similar to Escitalopram and Sinus node dysfunction :

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on escitalopram oxalate (the active ingredients of Escitalopram) and Escitalopram (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.