Ibuprofen and Synovitis - a phase IV clinical study of FDA data

Summary:

Synovitis is reported as a side effect among people who take Ibuprofen (ibuprofen), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Enbrel, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Synovitis when taking Ibuprofen. It is created by eHealthMe based on reports of 239,218 people who have side effects when taking Ibuprofen from the FDA, and is updated regularly.

What is Ibuprofen?

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,263 Ibuprofen users. Check the latest studies of Ibuprofen.

What is Synovitis?

Synovitis (inflammation of the synovial membrane) is found to be associated with 714 drugs and 504 conditions by eHealthMe. Check the latest studies of Synovitis.

On Jan, 22, 2026

239,218 people reported to have side effects when taking Ibuprofen.
Among them, 3,447 people (1.44%) have Synovitis.

Among these 3,447 people:

* Approximation only. Some reports may have incomplete information.

Do you take Ibuprofen and have Synovitis?

- Check whether Synovitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ibuprofen:

Ibuprofen (245,263 reports)

Synovitis treatments and more:

Synovitis (24,130 reports)

How severe was Synovitis and when was it recovered:

Synovitis in Ibuprofen

Expand to all the drugs that have ingredients of ibuprofen:

Synovitis and drugs with ingredients of ibuprofen (3,653 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ibuprofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Synovitis:

Browse all the drugs that are associated with Synovitis:

Synovitis (714 drugs)

Common conditions associated with Synovitis:

Ra: 16,944 reports
Psoriatic arthropathy: 2,837 reports
Psoriasis: 2,098 reports
Crohn's disease: 820 reports
Juvenile rheumatoid arthritis: 734 reports
Pain: 687 reports
Alternative medicine - pain relief: 675 reports
Ankylosing spondylitis: 658 reports
Arthritis: 547 reports
Systemic lupus erythematosus: 503 reports

Browse all the conditions that are associated with Synovitis:

Synovitis (504 conditions)

Drugs similar to Ibuprofen and Synovitis :

Related publications that referenced our studies

Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .

How the study uses the data?

The study uses data from the FDA. It is based on ibuprofen (the active ingredients of Ibuprofen) and Ibuprofen (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.